Who is Sherpa?
Image credit: http://proof.nationalgeographic.com/2014/05/13/responding-to-tragedy-the-sherpa-fund/
What makes them super special than the rest of us here on 56m above sea level in Kuala Lumpur?
• At 2,400m above sea level – normal human will suffer acute mountain sickness [symptoms: rapid pulse, nausea or vomiting]
• At 2,500m above sea level – normal human will suffer from high altitude pulmonary edema [symptoms:
, rapid shallow breathing] dyspnea
• At 4,000m above sea level – intolerable to 40% less ATM environment. A normal human will suffer from high altitude cerebral edema [symptoms: altered mental state, retinal venous dilation]
? They reside at the altitude of 3,440m above sea level. them
But how is that possible?
They succeeded the EPAS1 gene [high altitude living] from archaic Denisovan people from 40,000 years ago, which regulates the body’s production of hemoglobin.
, the scientist thinks this trait helps them avoid clots and strokes caused when the blood thickens with more hemoglobin-laden red blood cells. low hemoglobin concentration
They have more elaborated blood
this helps to transport vessels hence of oxygen efficiently. smaller amount
As a conclusion, these super athletic humans can carry out normal life at 3,440m above sea
could easily be fatal for us normal human being. level which
Image credit: http://www.chebocheareatrust.org.nz/about_cheboche_village
Dyspnea : difficulty in breathing at rest
: mixture of snow climbing, ice or rock climbing & glacier travel
: protein molecule in red blood cells that carries oxygen
1. Genetic contribution of the endothelial nitric oxide synthase gene to high altitude adaptation in Sherpas (High Altitude Medicine & Biology, February 2006)
3. Medline Plus - https://www.nlm.nih.gov/medlineplus/ency/article/000133.htm